Study using SyMRI REMyDI published in American Journal of Neuroradiology (AJNR)
A study published in the American Journal of Neuroradiology used SyMRI REMyDI to estimate myelin volume, axon volume and the g-ratio in patients with Multiple Sclerosis (MS).
The study showed the myelin damage was more rapid than axonal damage in plaques and periplaque white matter of patients with Multiple Sclerosis, such that the g-ratio increased in lesions. The authors conclude that myelin and axon volume fractions and the g-ratio may be useful to objectively assess white matter damage in patients with MS.
“The study is important because it adds a step on the way to more objective decision support based on quantitative MRI,” says Dr Marcel Warntjes, CTO and founder of SyntheticMR. “Using quantitative measurements, a patient can be monitored more accurately, and this provides means for radiologists and neurologists to respond earlier to changes and treatment effects during the progress of a disease.”